The Asus Eee Top comes in two versions with the ET1602 and the ET1603. Inside the Asus Eee Top ET1603 a discrete ATI Mobility Radeon HD3450 is responsible for more graphics power, as compared to the ET1602, which enables the system to run graphically-intensive 3D applications and games more fluidly. Even though the Asus Eee all-in-one desktop has touch-sensitive screen, it still comes bundled with keyboard and mouse.Setting up the Eee Top is as easy as taking it out of the box and plugging it in. This system is also the perfect computer for beginners. It features an exclusive Easy Mode within Windows that makes commonly-used applications easily accessible. With its sharp and vibrant widescreen (16:9) LCD, the Eee Top becomes the perfect Media Entertainment Center. Asus´s patient Splendid Video Intelligence Technology renders the video display with a vivid and clear image regardless of environmental lighting and SRS technology works in tandem with the Eee Top´s built-in high fidelity speakers to deliver crystal clear audio.The Eee Top touchscreen PC is first to ship in Taiwan, Hong Kong and the UK. In 2009 Asus is also adding larger screen models with 20- and 22-inch Asus Eee Top PCs. There is no information yet as to when these PC´s will be available in the US. Mini-PC-Pro Reviews ASUS Eee Top PC in a live demonstration. © 2008 PhysOrg.com (PhysOrg.com) — Asus has just revealed their 15.6-inch Eee Top touchscreen PC that is powered by an Intel Atom processor N270 (1.60GHz) and Intel 945 GSE core-logic with built-in graphics core. The system features a 160GB hard drive, 1GB of RAM, 4-in-1 card reader, integrated camera, Wi-Fi 802.11n controller and Windows XP Home operating system. Explore further Cute, efficient Eee Top looks like future of home computing Citation: ASUS Eee Top Touchscreen PC’s Coming 1H 2009 (2008, November 25) retrieved 18 August 2019 from https://phys.org/news/2008-11-asus-eee-touchscreen-pc-1h.html This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only.
The rock python is “vicious”, according to Kenneth Krysko of the Florida Museum of Natural History. It is even meaner than the Burmese pythons, which have been known to eat alligators, and which have already taken up residence in the nearby Everglades National Park, where they have wiped out thousands of native animals. Another major alien in the park is the boa constrictor.Six specimens of Africa’s longest snake have been discovered in a single square mile west of Miami, Florida, since the first was sighted in 2002. Krysko believes the original snakes may have been released by pet breeders when they grew too big, or when the breeders were surprised by their aggressiveness. The finding of two hatchlings and a pregnant female suggests the snakes are settling in.The rock python, like the Burmese python and boa constrictor, is not poisonous but kills its prey by constricting it and suffocating it to death before swallowing it.With the Everglades National Park just across the road, the rock python may already have joined the other giant aliens in the park in wiping out the native fauna. According to Robert Reed of the U.S. Geological Survey in Colorado, the new snake might eat any warm-blooded animal it can ingest. The Burmese python is known to eat dozens of species, including white-tailed deer and even six-foot alligators, and Reed expects the rock python to do the same.Another potential problem is inter-breeding of the African rock python and the Burmese python to produce a hybrid species. This has been known to happen in captivity, and while most such offspring are infertile, there is a possibility that offspring of the two species could be even hardier and more deadly than their parents, according to Reed.Kristina Serbesoff-King of the Nature Conservancy in Florida said that we should learn from past mistakes and try to eliminate the rock python while it is still confined to a relatively small area. One approach could be a python patrol, similar to the one the Nature Conservancy ran to try to reduce the numbers of Burmese pythons.If the African rock python is not stopped in its tracks, the scientists agree the problem may be even worse than the Burmese python problem because the rock python is far more aggressive. In its native home the African rock python is known to attack humans, according to Krysko, and if hidden in a swamp, it could strike before you even knew it was there. It could pose a particular danger for pets and small children.© 2009 PhysOrg.com (PhysOrg.com) — New studies suggest a 20 foot snake, the African rock python, is making its home in Florida and could soon invade the Everglades National Park. Python molurus bivittatus. Image: Wikipedia. Explore further Citation: ‘Vicious’ Giant Python Invading Florida (2009, September 21) retrieved 18 August 2019 from https://phys.org/news/2009-09-vicious-giant-python-invading-florida.html Fla. governor approves plan to capture, kill Burmese pythons This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only.
As it turns out someone with some serious skills also wanted that. Cesar Herada, a researcher who has formerly been associated with Ushahidi and MIT’s Senseable City Lab, has created the Protei oil-spill cleaning drone. The Protei oil-spill cleaning drone is designed to be a semi-autonomously device that can sail into the sea and scoop up the oil in a spill, leaving the oil in the container and the water in the ocean. How is this accomplished? With the help of powerful oil-sucking booms that are built into the device. The oil-sucking boom is detachable, and each one is able to hold up to two tons of crude oil per trip. The advantage to using one of these devices is that no humans have to be exposed to toxic substances in order to clean up the mess. © 2010 PhysOrg.com (PhysOrg.com) — Oil spills represent a significant danger to the oceans of the world. Many of us watched the DeepWater Horizon Oil Spill in the Gulf of Mexico and wished that there was a simple way to clean it up. Citation: Cesar Herada designs oil sucking drones to help clean the seas after a spill (2011, April 12) retrieved 18 August 2019 from https://phys.org/news/2011-04-cesar-herada-oil-drones-seas.html Explore further More information: sites.google.com/a/opensailing.net/protei/ The Protei drones are also able to be modified for other types of disasters. In the future modified versions of the Protei drones may possibly be sent in to detect the levels of radiation in water supplies, or to collect samples of other potentially polluted waters. The designers have also mentioned that there may be some commercial uses for the Protei drones as well, but they did not give any specifics on this point. Clean-up tools may help protect wetlands from Gulf of Mexico oil spill The best part is that Protei is an Open Source Hardware project. This means that its design will be available to the public, so it can be built by anyone. The remote controlled Protei is relatively inexpensive to produce and inflatable. This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only.
© 2012 PhysOrg.com Then Kaspersky’s Fabio Assolini, a lab expert, said one bit of malware especially caught his team’s attention because the malicious extension was hosted on Google’s own Chrome Web Store. “At this time,” Assolini said in a March 23 blog, “the malicious app has 923 users.”The extension presented itself as Adobe Flash Player. After installation, the extension could gain complete control of the victim’s profile first by downloading a script file. The script file had instructions to send commands to the victim’s Facebook profile. The result was the eventual spread of a malicious message, inviting more users to install the fake extension. So what’s in such a scheme for the malware makers? Profit, in the form of selling Facebook “likes” to businesses looking for (ironically) a reputation boost and may be willing to pay the $27 charged for 1,000 “likes.”According to reports, Google personnel removed the malicious extension after Kaspersky informed them of the hustle – titled Trojan.JS.Agent.bxo—which the Kaspersky experts had discovered on March 6 in a previous similar attack.According to Ars Technica, a Google response was, “When we detect items containing malware or learn of them through reports, we remove them from the Chrome Web Store and from active Chrome instances. We’ve already removed several of these extensions, and we are improving our automated systems to help detect them even faster.” Beyond the Store, one security plus for Google was the launch, earlier this year, of Bouncer, which scans the Android Market for malicious apps. The scan happens when developers first upload an app to the Market and then periodically after that.The Bouncer safeguard does not, however, seem to console observers over thieves who find ways to outsmart Facebook and Google.Those behind the cash-for-likes scheme “are uploading new extensions regularly, in a cat and mouse game,” said Kaspersky’s Assolini.Kaspersky Lab noticed a “huge wave” of attacks in Brazil. Without naming the miscreants, Assolini’s column warning users to “think twice” before installing Chrome extensions simply referred to “Brazil’s bad guys” turning their attention to Chrome and Facebook, which are now Brazil’s two key go-to places on the Internet. Recent statistics show that Google Chrome has become the most popular browser in Brazil with more than 45 percent of market share. Facebook is the most popular social network in Brazil, with 42 million users, displacing Orkut. This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only. More information: www.securelist.com/en/blog/208 … ng_Chrome_extensions Microsoft anti-virus program evicts Chrome browser (PhysOrg.com) — A cash-for-Facebook’s-“likes” hustle hanging out in Google Chrome Web Store has been discovered by Kaspersky Lab. The researchers first discovered extensions leading to the wave of hijackings under an umbrella of assorted themes that were targeting users of Chrome and Facebook. They were rolling out malicious extensions for use to nab Facebook profile data. The lure was in the form of invitations for users to make changes on their profile or to see who was visiting their profile or to remove a virus from their Facebook profile. Citation: Shoplifters hit up Chrome Store for Facebook data (2012, March 28) retrieved 18 August 2019 from https://phys.org/news/2012-03-shoplifters-chrome-facebook.html Explore further
Play Movie of nanoparticles moving through mucus. Credit: Schneider et al. Sci. Adv. 2017;3:e1601556 The nanoparticles, the team notes, were created using biodegradable materials that prior research found safe for internal use. Testing in mice, they report, showed the particle carriers stayed in the lungs for several hours—they also proved to be more effective than conventional therapies at reducing asthma symptoms such as irritation. The researchers suggest that MPPs could offer a better treatment plan for lung patients by providing a therapy that maintains drug levels in the lungs for longer periods of time, reducing the need for repeated dosing, which itself can cause lung irritation. PausePlay% buffered00:0000:00UnmuteMuteDisable captionsEnable captionsSettingsCaptionsDisabledQuality0SpeedNormalCaptionsGo back to previous menuQualityGo back to previous menuSpeedGo back to previous menu0.5×0.75×Normal1.25×1.5×1.75×2×Exit fullscreenEnter fullscreen More information: Craig S. Schneider et al. Nanoparticles that do not adhere to mucus provide uniform and long-lasting drug delivery to airways following inhalation, Science Advances (2017). DOI: 10.1126/sciadv.1601556AbstractMucoadhesive particles (MAP) have been widely explored for pulmonary drug delivery because of their perceived benefits in improving particle residence in the lungs. However, retention of particles adhesively trapped in airway mucus may be limited by physiologic mucus clearance mechanisms. In contrast, particles that avoid mucoadhesion and have diameters smaller than mucus mesh spacings rapidly penetrate mucus layers [mucus-penetrating particles (MPP)], which we hypothesized would provide prolonged lung retention compared to MAP. We compared in vivo behaviors of variously sized, polystyrene-based MAP and MPP in the lungs following inhalation. MAP, regardless of particle size, were aggregated and poorly distributed throughout the airways, leading to rapid clearance from the lungs. Conversely, MPP as large as 300 nm exhibited uniform distribution and markedly enhanced retention compared to size-matched MAP. On the basis of these findings, we formulated biodegradable MPP (b-MPP) with an average diameter of <300 nm and examined their behavior following inhalation relative to similarly sized biodegradable MAP (b-MAP). Although b-MPP diffused rapidly through human airway mucus ex vivo, b-MAP did not. Rapid b-MPP movements in mucus ex vivo correlated to a more uniform distribution within the airways and enhanced lung retention time as compared to b-MAP. Furthermore, inhalation of b-MPP loaded with dexamethasone sodium phosphate (DP) significantly reduced inflammation in a mouse model of acute lung inflammation compared to both carrier-free DP and DP-loaded MAP. These studies provide a careful head-to-head comparison of MAP versus MPP following inhalation and challenge a long-standing dogma that favored the use of MAP for pulmonary drug delivery. Play Movie of nanoparticles moving through mucus. Credit: Schneider et al. Sci. Adv. 2017;3:e1601556 Citation: Nanoparticles pass through mucus membranes in lungs to deliver pulmonary drugs (2017, April 6) retrieved 18 August 2019 from https://phys.org/news/2017-04-nanoparticles-mucus-membranes-lungs-pulmonary.html Journal information: Science Advances Lung problems impact the lives of millions of people. Such conditions include asthma, in which bronchi spasm, making it difficult to breathe; cystic fibrosis, in which over-production of mucus leads to blocking of bronchi; and COPD, in which obstructions form in bronchial passages. Fortunately, these types of ailments are all treatable to some degree, though they cannot be cured. For that reason, scientists continue to look for ways to improve current therapies.Currently, lung ailments such as cystic fibrosis, COPD and asthma are treated with inhaled drugs such as corticosteroids that adhere to the walls of air passages. In some instances, they are carried by what are known as mucoadhesive particles, (MAPs), but, as the researchers note, thick mucus often builds up on such passageways, lessening the effectiveness of the delivery system. In this new effort, the researchers took a different approach—rather than trying to make medicines that adhere do their job better, they turned to nanoparticles that are small enough to make their way through mucus membranes to the lining of the lungs themselves, offering direct medication application to affected areas. Called mucus-penetrating particles (MPP), they remain in the lungs, releasing medication for an extended period of time. The making of mucus in common lung diseases PausePlay% buffered00:0000:00UnmuteMuteDisable captionsEnable captionsSettingsCaptionsDisabledQuality0SpeedNormalCaptionsGo back to previous menuQualityGo back to previous menuSpeedGo back to previous menu0.5×0.75×Normal1.25×1.5×1.75×2×Exit fullscreenEnter fullscreen This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only. © 2017 Phys.org Explore further (Phys.org)—A team of researchers from multiple institutions in the U.S. has developed a new way to treat lung disease—using nanoparticles to transport chemicals through the thick mucus membranes that can coat pulmonary airways. In their paper published in the journal Science Advances, the team describes how they used particles small enough to move through holes in the mesh that makes up mucus to deliver helpful drugs.
Re-engineering the cell membrane for improved biofunction is an emerging, powerful tool in cell biology to develop next-generation cell therapies. The process can allow users to supplement cells with added therapeutic functionalities. Additional functionalities can include cell homing, surface adhesion or resistance to hypoxia for enhanced cellular capabilities. However, the number of such examples on re-engineered plasma-membranes to activate membrane-bound enzymes that promote the assembly of extracellular matrix (ECM) proteins to promote cell functionalities are limited. 3D projection of fibrin gel containing fibrinogen stained with Alexa 594 (red) fibrinogen and hMSCs incorporating sc_thrombin [ox890] stained with Hoeschst 33342, imaged after 60 min of cell associated fibrin formation in cell culture. Credit: Nature Communications, doi: 10.1038/s41467-019-09763-0. They synthesized the artificial membrane binding thrombin complex using a two-step process to generate an active supercationic thrombin construct (sc_thrombin). Deller et al. also generated a polymer surfactant corona or green halo using electrostatic coupling of glycolic acid ethoxylate 4-nonylphenyl ether (ox890) to sc_thrombin to engineer a third variant sc_thrombin [ox890]. The scientists controlled the reaction conditions (pH, temperature and chemical composition) carefully and monitored the reaction progress using zeta potentiometry across a period of two hours. They observed the activity of thrombin by monitoring/characterizing the increasing turbidity of the fibrinogen solution. They then obtained MALDI-TOF spectra (matrix-assisted laser desorption ionization time of flight mass spectroscopy) of the native and modified thrombin to show full cationization of the construct. When Deller et al. conducted compression testing of the resultant self-supporting structures, the Young’s moduli were similar to soft fibrin hydrogels, indicating consistency. To investigate thrombin adhesion to cell membranes, the scientists chose a monolayer of bone marrow derived hMSCs (with well-characterized adipogenic, chondrogenic and osteogenic pathways). First, they incubated a monolayer of hMSCs with fluorescently-labelled analogues of thrombin; thereafter, they labeled the hMSCs with a plasma membrane-specific dye and imaged immediately to confirm the thrombin-plasma membrane binding. Using time-lapse confocal fluorescence microscopy, they showed the nucleation and fibrin growth from the cells thereafter. Welding with stem cells for next-generation surgical glues Advanced cell therapies are currently approaching clinical translation in response to an increasing demand for newly modified, cell-specific matrices (scaffolds) for biocompatible therapeutic performance. However, the rational design of matrices is extremely challenging since the cell phenotype and cell fate can be intertwined to a wide-range of scaffold-dependent factors; including cell adhesion, surrounding chemical composition, cell receptor stimulation, surface micro-/nano-morphology and mechanical stiffness. These factors immediately impact cells during in vitro tissue engineering, typically when cells are seeded to adhere on biocompatible and biodegradable scaffolds in the lab, where the scaffolds act as a surrogate extracellular matrix (ECM). Eventually, when the cells grow and differentiate, they can produce natural ECM of their own, to gradually replace the biomimetic scaffold material and form a structurally self-supporting biological entity. Deller et al. also completed cell growth assays to determine relative metabolic activities of labelled hMSCs-thrombin to show the modified cells were without observable cytotoxicity in varying concentrations of thrombin (1 µm to 25 mM). Using confocal microscopy again, the scientists showed the arrangement of fibrin structures emanating from the plasma membrane of the hMSC monolayer, in contrast to hMSCs without thrombin. The work protocol thereby generated a 3-D fibrin hydrogel construct with dense cellular aggregates surrounded by a 3-D fibrin matrix. The scientists also investigated the ability of the fibrin hydrogel system to sustain 3-D cultures for long-term growth; a requisite for tissue engineering, to show hMSC differentiation via adipogenic and osteogenic pathways. To verify the results, the scientists conducted extensive biomechanical tests on the cell types and tested for the upregulation of specific genes SOX9 and RUNX2 involved in chondrogenesis and osteogenesis respectively, using RT-PCR (reverse transcription polymerase chain reaction), to substantiate the fibrin hydrogel system sustained long-term hMSC proliferation in vitro.After confirming the membrane re-engineering approach for in lab tissue engineering applications, Deller et al. investigated the ability to produce thrombin coated cells in lab for their injection at a site of injury to initiate a healing response for tissue-engineering applications in vivo. For this, the scientists used an in vivo Zebrafish model system to perform preliminary cell transplant studies. Zebrafish is a model organism, established for fluorescently labelled live cell imaging and thrombolytic and hemostatic processes; suited for the present work. The scientists isolated, labelled and delivered fluorescently labelled primary Zebrafish fibroblasts, labelled with sc_thrombin[ox890] conjugate via microinjection to show cell survival after 3 days at a site of incisional injury. The synthesis and characterisation of the supercationic thrombin-polymer surfactant conjugate. a Schematic showing the electrostatic surface potential of native and supercationic thrombin (sc_thrombin) (PDB; 1UVS) at pH 7, highlighting the anionic (blue) and cationic (red) charged regions. Generation of the polymer surfactant corona (green halo) via electrostatic coupling of glycolic acid ethoxylate 4-nonylphenyl ether (ox890) to sc_thrombin gives [sc_thrombin][ox890]. b Zeta potential (ca. pH7; n = 3) of thrombin as a function of cationization times (0–120 min). Data reported as means ± standard deviation (s.d.). c Rate of fibrinogen solution (3.125 mg mL−1) gelation as measured by changes in turbidity (600 nm) catalysed by sc_thrombin subjected to various cationization times (0–120 min). Data shown as one-phase association curves of raw data. d MALDI-TOF MS spectra (m/z = 3) of native and sc_thrombin (60 min). Credit: Nature Communications, doi: 10.1038/s41467-019-09763-0 Schematic diagram showing in situ fibrin hydrogel formation from the membranes of bone-marrow derived human mesenchymal stem cells (hMSCs). Artificial membrane binding thrombin constructs comprising supercationic thrombin molecules (white) surrounded by a polymer surfactant corona (yellow) that associates with surface exposed cationic (red) residues spontaneously insert into bilayer regions of hMSC plasma membranes. In the presence of fibrinogen, the membrane-immobilised thrombin catalyses fibrin formation (blue fibres) within the interstitial spaces between the cells giving rise to a self-supporting hydrogel monolith. Credit: Nature Communications, doi: 10.1038/s41467-019-09763-0 More information: Robert C. Deller et al. Artificial cell membrane binding thrombin constructs drive in situ fibrin hydrogel formation, Nature Communications (2019). DOI: 10.1038/s41467-019-09763-0 D. E. Discher. Tissue Cells Feel and Respond to the Stiffness of Their Substrate, Science (2005). DOI: 10.1126/science.1116995 Tamer A.E. Ahmed et al. Fibrin: A Versatile Scaffold for Tissue Engineering Applications, Tissue Engineering Part B: Reviews (2008). DOI: 10.1089/ten.teb.2007.0435 © 2019 Science X Network In a recent study, Robert C. Deller and co-workers at the interdisciplinary departments of Cellular and Molecular Medicine, Engineering, Functional Nanomaterials and Pharmacology, and Neuroscience in the UK, bioengineered a self-contained cell matrix-forming system. In the experiments, they modified the plasma membrane of human mesenchymal stem cells (hMSCs) to integrate a new thrombin construct, which gave rise to spontaneous fibrin hydrogel nucleation and growth when supplemented with human plasma concentration levels of fibrinogen in cell culture media. The scientists bioengineered the cell membrane by synthesizing a membrane-binding supercationic thrombin-polymer surfactant complex. Thereafter, they observed cell differentiation in the resulting robust, stem cell-containing fibrin hydrogel constructs to form osteogenic and adipogenic cell lineages. The differentiated cells could eventually secrete fibrin to form self-supported bioengineered cellular monoliths that exhibited Young’s moduli as expected of the native extracellular matrix. The results are now published in Nature Communications. A range of natural biocompatible polymers have produced such transient hydrogel scaffolds for tissue engineering; including chitosan, gelatin and fibrin. Fibrin hydrogels are the most popular among them, since they can be produced readily at room temperature using proteolytic cleavage. Biological fibrin formation occurs in response to injury, culminating from a biochemical cascade of proteolytic cleavage, which converts prothrombin to thrombin and forms a fibrin-hydrogel clot. Fibrin hydrogels can therefore mediate cellular biomolecular functions and regulate the osteogenic and chondrogenic differentiation of human stem cells such as hMSCs. They can also be conveniently delivered using syringes, albeit with complications related to reduced cell viability.In the present work, Deller and co-workers first described a method to synthesize supercationic thrombin-polymer surfactant complexes that spontaneously bound to the plasma membrane of hMSCs to drive in situ fibrin hydrogel nucleation and growth. The resulting self-supporting hydrogel construct allowed high levels of metabolic activity as an artificial matrix for effective differentiation of stem cells to form adipogenic or osteogenic cell lineages. The scientists then showed the feasibility of the method of cell functionalization by injecting thrombin-labelled GFP-expressing fibroblasts (GFP: Green fluorescence protein) into a zebrafish (Danio rerio) skin wound model to demonstrate their in vivo biocompatibility for hemostatic applications. Explore further Journal information: Nature Communications In vivo zebrafish injury and [sc_thrombin][ox890] labelled GFP + fibroblast addition. Schematic representation of the in vivo adult zebrafish injury model. a Wildtype (non-transgenic) recipient zebrafish were anaesthetized and a 4 mm incisional injury made on the ventral upper thorax. A lateral view is shown. b Unlabelled or [sc_thrombin][ox890] labelled, FACS sorted GFP+ fibroblasts were injected at six sites around the edge of the incisional injury. At the desired time-point, fish were sacrificed and the tissue surrounding the incision was fixed, imaged and embedded for sectioning. A ventral view is shown. Ventral view of the area of tissue surrounding the incision at 3 dpi following transfer of c unlabelled or d [sc_thrombin][ox890] labelled GFP+ fibroblasts. Similar numbers of cells were retained at all wounds. The red line depicts the approximate position of the incisional injury which is fully re-epithelialized at this stage. Sections through the injury region at 3 dpi following transfer of e unlabelled or f [sc_thrombin][ox890] labelled GFP+ fibroblasts. No obvious differences were observed between wounds containing labelled or unlabelled cells. Arrows indicate the position of the incision. Credit: Nature Communications, doi: 10.1038/s41467-019-09763-0. Citation: Engineering artificial cell membranes to drive in situ fibrin hydrogel formation (2019, May 6) retrieved 18 August 2019 from https://phys.org/news/2019-05-artificial-cell-membranes-situ-fibrin.html Using macroscopic observations and histological assays, the scientists further revealed that there were no adverse effects between fish injected with engineered or native fibroblasts. However, Deller et al. expect to complete further investigations to understand the precise effects on the specific wound healing response using bioengineered cells in the future.In this way, Deller et al. synthesized and characterized a new membrane active thrombin construct and demonstrated its application to drive in situ fibrin formation in the plasma membranes of stem cells. The scientists showed that thrombin-based fibrin hydrogel constructs prepared using the new protocol supported high levels of cell growth and viability to eventually produce a self-supporting tissue engineered construct. The stem cells were also able to differentiate along the well-defined adipogenic and osteogenic pathways while demonstrating Young’s moduli similar to the native cells to indicate high levels of integration of the modifications. Deller et al. propose to optimize the protocols for further experiments in vitro prior to in vivo translation, to gain further insight to the enzymatic activity of cell membrane bound bioengineered proteins to develop biocompatible, hemostatic products. Evaluating rhodamine (rh) labelled rh_thrombin, rh_sc_thrombin and [rh_sc_thrombin][ox890] on hMSC plasma membrane affinity. Cells labelled with CellMask (green) and rhodamine labelled thrombin (magenta) visualized with confocal microscopy. Video shows the rh_sc_thrombin [ox890] labelled hMSCs supplemented with fibrin gel conjugating with fibrinogen (green) to highlight fibrin formation emanating from the bioengineered cell surface. Credit: Nature Communications, doi: 10.1038/s41467-019-09763-0 , Science This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only.
Come August and Monsoons shall turn magical in Kolkata, as the city gears up to host the third edition of Monologues, India’s only solo arts festival. The festival, hosted by Phreedom4Ever, an organisation led by Chaity Ghosh, that envisages cultural excellence, is the brainchild of popular elocutionist and theatre actor Sujoy Prosad Chatterjee. Being the only annual solo arts fiesta in the country, the forum has witnessed performances by stalwarts like Chapal Bhaduri (India’s last living female impersonator in performing arts), Saoli Mitra(the legendary actress and daughter of theatre maestro Shambhu Mitra), Mahabanoo Mody Kotwal, Bijoylakshmi Barman and many others over the last two years. The 2014 edition of Monologues shall kick off on 3 August at Swissotel with a solo by Mita Vashisht, who is an internationally acclaimed film personality. This is the first time that Mita shall present a theatrical performance in Kolkata and her act for the evening is called Weekend, a part of the very famous Teen Ekaant by novelist and activist Nirmal Verma, a noted figure in the Indian literary circles. Sujoy has always brought performances out of proscenium to alternative spaces and this festival endorses that. Also Read – ‘Playing Jojo was emotionally exhausting’Monologues 2014 showcases The Solo Room, the youth- section of the festival, on 9 August at Tantra, The Park as a matinee performance. Infact, Monologues is the only national arts festival that has a special segment dedicated to the youth and the arts. The Solo Room begins with an original dramatic act by Soumya Mukherjee, a very popular youth actor and the founder of M.A.D., a key youth-theatre player in Kolkata. Next on the cards shall be a musical solo by Kabir Chattopadhyay, who will entrance the audience with a whole lot western retro. The final act for the evening is a session of original lyrics and songs by the iconic music composer and vocalist Neel Adhikari. The finale of Monologues 2014 shall be on 10 August at Tollygunge Club. The evening begins with a solo comedy by much-admired media personality Anubhav Pal. What follows is a contemporary dance solo by internationally famous contemporary danseuse Paramita Saha, who shall revisit issues of gender construction through her performance. The crowning act shall be by the legendary Indian theatre personality and activist Usha Ganguly, who shall be premiering her new play Rozana, a monologue inspired by works of Franca Rame and Dario Fo. Going solo becomes an expression of a trajectory of emotions that sums up life and art. No wonder, this solo arts carnival has become the nation’s delight.
For long, the intimacy of a voice has been pivotal during travel sojourns, walk in the woods, congested drives, after fights with your best friend, in crowded marketplaces or even when you are all by yourself.This is none other than the radio jockeys giving you company with intermittent beauty tips, social issues, interactive debates and of course good, old melodies. With the benefit of hindsight, the radio has changed over the years. From news-based transmissions to today’s all-encompassing caucus of over-zealous listeners participating in a vast range of discourses. Also Read – ‘Playing Jojo was emotionally exhausting’RJ Siddharth from Big FM, Mumbai, says, ‘The change has been phenomenal. What started as an entertainment based format with the advent of private FM industry in the early 2000 has taken a giant leap to become a revolution involving each and every strata of society perhaps becoming the only format catering to the infotainment needs of individuals. And the biggest change that has happened is the pin-pointed and targeted programming at the most local level in a language they understand and giving a never-heard-or-seen-before opportunity to both the parties – advertisers and consumers (say listeners).’ Also Read – Leslie doing new comedy special with NetflixHe further adds, ‘Today’s radio jockeys should be the voice of the city and the people. It is essential for an RJ to have an opinion. They should be honest and of course need to have an in-depth knowledge on the issue/topics he is talking about. Pretence is something which must be avoided at any cost.’There is a lot to achieve and lot to explore vis-a-vis radio industry and the radio market are concerned. With almost 13-14 years of its existence, there is an ample space to bring in languages, different formats, music and personalities to make an inroad into segments where radio is yet to make its presence felt. Speaking about the essential elements of radio, he says, ‘Understandably, music and especially film music is an essential part of radio and unlike western countries where private FM is immensely popular, film music is a genre in itself and we can’t visualize entertainment without taking it into account. We are working on an infotainment format hence music is there to stay till the time we find a suitable and more effective alternative.’India’s radio industry is undergoing a makeover with the government’s approval to allocate new radio licences through e-auction and increased foreign investment limit. This move will boost advertising revenue in the long-run, promote business consolidation and lower expansion cost, according to analysts and industry experts.According to RJ Koushik Bhattacharya from Kolkata, ‘There has been resurgence in the popularity of radio. The radio boom has thrown open a number of avenues and opportunities for young, energetic and enthusiastic people who have an ear for music and a passion to entertain. This has become a wonderful career for different professionals. At the same time, day by day, number of listeners is increasing from different sphere of life.’For RJ Prateek Sharma, who works with BIG FM 92.7 in New Delhi, the Indian radio industry is expanding by leaps and bounds. ‘The government is also being very helpful in the expansion of this medium. Norms are changing, reach is increasing, more and more people are tuning in, and many more brands are associating with the radio as a medium. Good and better days lie ahead certainly.’Prateek is one person who has worked in the international market and feels, ‘I think the response has been very encouraging. The kind of music that Indian radio stations play and the content that we provide, there is a big audience, ready to consume it. And if that music and content helps them to stay in touch with their Indian roots, what more can one ask for!’
Kolkata: Bandhan-Konnagar, a not-for-profit organisation, registered under the West Bengal Societies Registration Act, 1961 celebrated its ‘Development Day’ on Thursday, completing 18 years of service at ITC Sonar. Commencing its journey in the year 2001, the organisation has transformed the lives of around 1.8 million families spread across 11 states of India – West Bengal, Bihar, Odisha, Telangana, Jharkhand, Madhya Pradesh, Uttar Pradesh, Rajasthan, Assam, Also Read – Heavy rain hits traffic, flightsTripura and Chhattisgarh. The organisation has 818 field offices spread across 10,793 villages. More than 2,300 employees are actively involved in the welfare of the disadvantaged families.The Development Day event was graced by Craig L Hall, Honourable US Consul General, Kolkata along with many distinguished guests like Debasish Sen, Additional Chief Secretary, IT & Electronics and Chairman, HIDCO, Saurabh Das, Principal Secretary, Panchayat & Rural Development Department, Also Read – Speeding Jaguar crashes into Merc, 2 B’deshi bystanders killedDushyant Nariala, Principal Secretary, Department of School Education and other luminaries. In the welcome address at the event, Chandra Shekhar Ghosh, Founder & Mentor, Bandhan-Konnagar said: “All our development programmes are designed and implemented with the intent of supporting the underprivileged. The organisation is putting in honest and dedicated efforts to provide necessary holistic support to the marginalised ones. My heartfelt thanks to all our donors for reposing faith in us and to all those who support us in our journey of development.” A panel discussion was held on the topic: ‘Women Empowerment – Are we moving in the right direction’. Eminent journalist Suparna Pathak; Educationist & former Vice-Chancellor of Calcutta University, Professor Sugata Marjit, Executive Director, Action Aid India, Sandeep Chachra, Danseuse-cum-social activist, Alokananda Roy and Chairman, West Bengal State Commission for Women, Leena Gangopadhyay participated in the panel discussion.
Kolkata: The Kolkata Municipal Corporation (KMC) will impose heavy penalty on the responsible private firm if the four pumps that have gone for servicing, are not ready by July 10.Tarak Singh, member, mayor-in-council (drainage) who had visited two pumping stations at Behala, said the civic authorities will not spare the firm for the inordinate delay in servicing the pumps. He said there are five pumps at Begorkhal pumping station.On the day when it had rained heavily last week, one pump was found to be functional, while four others could not be operated as the repairer had not installed them after servicing. Also Read – Speeding Jaguar crashes into Merc, 2 B’deshi bystanders killedHe said there are three pumps at the Behala Flying Club pumping station. Of these, one pump was working while the second one had developed a snag and the third one had been sent for maintenance, on the day when it had rained heavily last week.He said The Kolkata Environmental Improvement Programme (KEIP) had engaged two firms to repair the pumps. Of the two firms, one has become bankrupt and the KEIP has written to the Asian Development Bank (ADB) to cancel the contract of the joint venture companies. It may be mentioned that Chief Minister Mamata Banerjee had called up Mayor Sovan Chatterjee on Sunday, expressing her displeasure over the delay in clearing accumulated water from some streets of Behala. Also Read – Naihati: 10 councillors return to TMC from BJPSome roads, lanes and bylanes at Silpara and Pora Asathwatala are still under water. In Sakherbazar, craters have come up on a stretch of Diamond Harbour Road. The potholes, which are covered with water, pose a serious threat to motorcycle riders and drivers.Senior KMC officials said patch repair will be carried out to cover up the potholes temporarily. Metro Railway is constructing the Joka BBD Bag Metro and because of the construction work, the underground pipeline has been damaged, causing waterlogging in some areas.
Darjeeling: Even before the biggest soccer battle took to the ground in Russia, miles away, the World Cup was handed over to Bara Kakjhora United Club in Darjeeling on Sunday afternoon.As part of the “Darjeeling World Cup Town 2018,” Darjeeling North Point School Alumni Association (DNPSAA) had announced that a World Cup replica would be handed over to the best decorated area of the town on the day of the finals.”Places like Aloobari, J P Sharma Path (Pachpan Hatta), Employment Exchange area, Nimki Dara and others were well decorated. However, Bara Kak Jhora was not just decorated well but was done with a purpose. The uniqueness lay in the informative flexes that were put up,” stated Deven Gurung, President of the DNPSAA. Also Read – Speeding Jaguar crashes into Merc, 2 B’deshi bystanders killedThe detailed history of the world cup including winners over the years; pictures and history of legendary football players; a special display of Sunil Chettri for his achievement in the intercontinental cup, matching the 64 international goals to that of Messi.”However, the most touching display was on the legendary players of Darjeeling titled – 60’s legendary players of Darjeeling. They had put up photographs of famous players like Chandan Singh Raut, Benu Subba, Avay Gurung, Krish Dewan, Raju Rai, Kapil Thapa, Shyam Thapa and others. Thus, we zeroed in on Bara Kakjhora United Club (BKUC),” stated Gurung. Also Read – Naihati: 10 councillors return to TMC from BJPThe world cup replica was handed over to members of the BKUC in Darjeeling.”It’s our honest endeavor to educate Gen Y in Darjeeling about Darjeeling’s rich football past. This land has created legends. The youth have heard of Messi but not of local legends. It is our effort to revive the rich football past by promoting local football,” stated Yogesh Bomzan, member of the BKUC.DNPSAA had organised the event “Darjeeling the World Cup Town 2018,” to raise funds for the outreach program Fr Van Memorial Clinic on wheels.It was just a one-day event on 2nd June 2018.The event was very successful with thousands of people participating in the football parade followed by a variety entertainment programmes at Chowrasta.The Clinic on Wheels will provide medical facilities in far flung areas, catering specially to the marginalised section of society.
To realise his aspiration of becoming a pure “Kalkatta-wallah”, the protagonist of this tale of a fervent, pervading desire for belonging and acceptance is advised to follow four key rules – believe that you know everything, accept rumours are more important than facts, make a grand gesture every now and then and most importantly, have a low enough ambition to be envious of those with higher ones. But can he follow them without irrevocably losing his identity and moorings and will he survive the transition? Also Read – World War I’s forgotten violent aftermath and toxic legacyThis is the premise of acclaimed story-teller Kunal Basu’s latest work – a searing, visceral narrative of the life and aspirations of the under-privileged outsiders in a metropolis and how their success is only a thin line away from disgrace or worse!Jamshed Alam or Jami, who with his parents and polio-affected sister exchanged one limbo – a refugee camp for Bihari Muslims in Dhaka optimistically called “Geneva” – for one marginally better, a chaotically, colourful Kolkata tenement thanks to an uncle who is a ruling Communist Party leader in the city and his zari factory-running mother, has one fixed dream – becoming a pukka Kalkatta-wallah. Also Read – Enid Blyton’s adventures get even more mouth-wateringWith his childhood entanglement with a local gang leading to an unceremonious early exit from school, he becomes an assistant to a passport agent, who is also engaged in some dodgy work. A chance encounter with a lonely, high-society woman during the understaffed Durga Puja holidays at the travel agency where he is working seems to open the door to a world of luxury and privilege and more so after she introduces him to a friend who runs a massage saloon with “other benefits” and he takes to this work with gusto. A world of the rich and famous – and the kinkily dangerous – is now accessible but also heightened is the danger from jealous rivals, police, and most from the world he grew up in.After he meets again and befriends a former co-worker – a single mother with a sick boy, Jami’s various worlds – family, neighbourhood and the gang, massage and other ‘services’ clients, and the world of culture he sought to become part of and succeeded to some extent though at a personal cost – collide after the old familiar things change in 2011, the cat-and-mouse games of terror and security rear their head, and he is at the marked risk of losing all that is dear to him and has painstakingly worked for, and even his very existence. Playing key roles in his chaotic journey are a multitude of well-drawn characters – his ulcer-suffering father, his hard-working but determined mother, his clear-thinking but sarcastic sister Miriam, Uncle Mushtak, the Communist party fixer (who is later dethroned), Jahanara, the local temptress, Rakib, the near psychotic gang-leader, Rajesh Sharma, the travel agent whose apprentice he becomes, Ani Mitra, his first Bengali friend and fount of wisdom for the city, Mrs Goswami who changes his life, Rani, the hijra who manages the massage parlour, and Mandira and Pablo, who not only make an empathetic human but also ultimately endanger him.Basu’s narrative is not a very comforting – in fact, is most unsettling – account of aspirations of migrants to become an anonymous part of a big metropolis where they land up in the hope of sustenance and once managing to climb out of the flotsam and eke out a basic livelihood, not matter how deprived and how filled with small and big acts of treachery towards loved ones and others, to dream to achieve some part of the opulently plush lifestyle they see around them and help to facilitate for the better-off.A key plot is also the basic absurdity of subcontinent’s affairs – farcial had it not been tragic – that runs through the principal protagonist’s origins. His family fled their ancestral home to a nearby part of a new country where they could be safe and prosper, but soon found themselves unwanted and under a new threat when this itself became a new country, and were forced to seek refuge again in the very country they originally fled from – and in a city which is anything but a City of Joy for them.It is a picture of Kolkata at its most unsympathetic and unwelcoming – and from a viewpoint most should thank for being spared – but still necessary viewing. Don’t shirk it! IANS
Kolkata: The state Agriculture Marketing department has set a target of setting up as many as 150 Sufal Bangla stalls by March 2019, after becoming successful in reaching its goal of opening 101 stalls.It may be mentioned that the department had set a target of setting up 101 Sufal Bangla stalls before Durga Puja. Recently, 21 movable and 5 static Sufal Bangla stalls have been inaugurated, which took the total number of such stalls to 101 across the state. Also Read – Rain batters Kolkata, cripples normal lifeSoon after reaching the target, the state Agriculture Marketing department has carried out an assessment to find out where it is still required to open such stalls. Subsequently, the decision has been taken to introduce another 50 stalls by the end of the 2018-19 financial year.Tapan Dasgupta, the state Agriculture Marketing minister, said: “Our endeavour is to open another 50 stalls by the end of March 2019.”The main idea behind setting up Sufal Bangla stalls is to help common people staying in the urban or semi-urban parts of the state get fresh vegetables at the right price. At the same time, it also encourages setting up of more Farmers Production Organisations (FPOs). Farmers, who are members of the FPOs, directly supply their produce to the Sufal Bangla stalls that get sold at the right price. As a result, farmers no longer need any middlemen to sell their produce. They also get the right price for their produce and do not incur loss. Also Read – Speeding Jaguar crashes into Mercedes car in Kolkata, 2 pedestrians killedThere are both static and movable Sufal Bangla stalls. The static ones are situated mainly in urban and semi-urban areas in the state, while the movable ones keep travelling at different points within a particular area to sell fresh vegetables.Officials of the state Agriculture Marketing department has initiated the task of identifying the places where static ones can be set up and where there is requirement of movable ones.It may be mentioned that price of vegetables and other items, which are available in Sufal Bangla stalls, is available in the website of the Agriculture Marketing department. After checking the price, one can also place order over phone for home delivery, which is available in some of the stalls. The department is also taking steps to introduce the home delivery service in all of its stalls.
If you are an infrequent internet user, then mere presence of a smartphone can adversely affect your cognitive performance, a study has found.“The mere presence of a mobile phone was a distraction among infrequent internet users,” said Jun-ichiro Kawahara, Associate Professor at Hokkaido University, Japan.The researchers also found that people who are often glued to a screen are not easily distracted by the presence of a cell phone.In presence of a mobile phone, people are automatically drawn to it and then the individual differences decide how they attempt to ignore it. Also Read – Add new books to your shelfResearchers measured the effect of mobile phones on the ability to pay attention of 40 undergraduate students divided into two groups.The researchers placed a mobile phone next to a computer monitor, asked the participants of one group to search for a target character amongst other characters that appeared on the monitor screen. For the another group, a memo pad of the same size as the phone was placed by the monitor, and the same experiment was conducted. Also Read – Over 2 hours screen time daily will make your kids impulsiveThe participants were asked about how frequently they use and how attached they are to the internet.The researchers found that people who infrequently used the internet took longer to find the target character than the control group.On the other hand, it was found that heavy users were not distracted by the phone and rather more efficient to notice the target when it appeared on the side of the monitor where the mobile phone was placed.The study – published in the journal Japanese Psychological Research – also suggests that the influence of a mobile phone on users’ cognitive performance differed depending on the degree of their internet usage.
Olive oil is the liquid goodness we reap from the olive. This tree crop is mostly found in the Mediterranean Basin and has a lot to offer to humankind. We use it in the kitchen, on our bodies, furniture and so many other places. Olive oil’s health benefits are commonly known but the interesting and gripping history behind it is rarely spoken about. Of the many theories behind the evolution of olive oil, two of the most interesting are: The Big Fat Greek Theory Also Read – Add new books to your shelfAthens is named for the Goddess Athena who brought the olive to the Greeks as a gift. Zeus had promised to give Attica to the god or goddess who made the most useful invention. Athena’s gift of the olive, useful for light, heat, food, medicine and perfume was looked greatly upon. Athena planted the original olive tree on a rocky hill that we know today as the Acropolis. The olive tree that grows there today is said to have come from the roots of the original tree. Homer, the Greek poet called it ‘liquid gold.’ Also Read – Over 2 hours screen time daily will make your kids impulsiveLight of JewsOlive oil lamp is the kind of lighting that was used in the Holy-land 2,000 years ago. It is the oil that was used in the Temple Menorah during both the first and the second Temple in Jerusalem. It was the oil that brought about the miracle of Hanukkah during the time of the Maccabees – over 150 years before Jesus was born and the oil that Jesus studied the Holy Scriptures by, in his childhood home in Nazareth.In Greece, they rubbed their bodies with this oil and it’s glow has illuminated it’s rich history, also the tree has been blessed with something close to immortality. They grow proud and strong no matter what harsh weather mother nature puts them through. This adds to it’s popularity , making it a household item. The benefits of olive oil are innumerable. From curing cancer cells to aiding hair growth to moisturizing the skin to removing the dirt from tiny nails. But an underrated concept of olive oil is its role in art. The main reason it is used for art is because Olive oil burns cleanly, without smoking. It doesn’t spread toxic hydro-carbons into the air. It is inexpensive and plentiful and a renewable lamp fuel. Instead of spending a fortune on decoration, using the bottle that contains the liquid gold is way more convenient. Olive Oil LampUsing pliers cut a 15 inch length of wire. Roll one end of the wire tightly around the nose of the pliers 4 to 6 times. Move to the other end of the wire and wrap a circle that will fit into the bottom of the jar that you’ve chosen for your lamp. Wrap this circle several times with the wire to make a firm foundation for your wick. Using tweezers, feed your wick through the circle made by the pliers, and pull through the top as in the photo. Place the wick in its holder in the jar. Fill with olive oil to within one inch of the top of the wick. Allow the wick to absorb olive oil to the top of the wick. This may take 10 minutes or more. Once the wick is saturated, light the wick with a match or candle and voila you have a olive oil lamp.Olive oil Painting Paint an empty wine bottle with non-toxic paint and fill with olive oil. Top with an oil pour spout that can be found at a gourmet cooking shop. Turn a wine bottle into an oil bottle Van Gogh on a wine bottleLemon-filled Olive Oil LanternsLoosely twist your wire around the wick leaving a small portion at the top in order to light on fire. Center your wick inside your container then bend the wire over the side to anchor it into place. You can buy special oil lantern wicks specifically to use with converting canning jars into lanterns. Then slice your lemons to your desired thickness and place them inside your container arranging them in a way to cover the sides without taking up the bulk of room inside the container. You want to fill it with as much oil as possible. After you’ve arranged your lemon slices the way you want, carefully fill the container with your oil. Not only are the lemons pretty but they also help scent the oil so it will give off a soft lemon fragrance the longer they soak in the oil.The real origin of the blessed olive is not certain but it is speculated to be from Syria or sub-Saharan Africa. For more than 6000 years, olive has developed alongside Mediterranean civilizations and is now commercially produced on more than 23 million acres in the Mediterranean basin. It is more just food or flavour for the people from the Basin. It is their identity and pride.Having been used for centuries, it is simply one of the least harmful fats in use no matter what our nutritional choices may be. It’s endorsement by all communities is the proof of it’s worth. Olive oil beauty products are a multibillion dollar business and its uses stretch far and wide – from human health to art – you name it, olive oil has a solution for it.
Suraksha Diagnostic Pvt Ltd (SDPL), a centre of innovation, is one of the trusted names in the healthcare industry with its unmatched international standards. Serving for almost three decades through its 41 centres all over the country is now proud to possess almost every possible diagnostic technology.Suraksha recently partnered with Clugenix – a San Francisco based biotech company focused on making translational genomics technologies accessible globally to the Indian population. Led by Dr Joydeep Mukherjee, a globally recognised, multiple award-winning researcher in oncology and infectious diseases genomics in Toronto and UCSF, Cluegenix will make available to Suraksha the latest developments in Molecular Biology. Also Read – Add new books to your shelfMore importantly, together they will work to set up the protocols for the Indian population in genomics. A lot of this research being done in the house will help to reduce the cost of these expensive tests considerably. They will be launching to design the Next-Gen Sequencing panel for Breast Cancer for Indian women as their first research project out of this JV. Suraksha has come up with ‘Aptio’ automation, the robotic track, as a unified and complete solution to its expanding need. The track is completely AI enabled and runs without human interference. It provides the best therapeutic turnaround time in the industry. In an emergency, it can churn out a report in less than a minute. The entire system is One flow One Touch. Also Read – Over 2 hours screen time daily will make your kids impulsiveThey have laid a track that can do Biochemistry and Haematology at the same time. ‘Aptio’ connects numbers of diagnostic analysers even of different principles or discipline. Its automated sample loading and handling (tube sorting, offloading) feature helps lab staffs to from time-consuming, low-value tasks. Staffs are also spared from segregating different types of samples (EDTA whole blood, serum, urine), one from each other. The track reduces pre-analytical errors by detecting any mismatch between test request and tube type, identifies problem samples and draws the attention of the operator. Simultaneous STAT and routine testing on a single track with optional front-loading for urgent or low volume samples to instruments enable lab supervisors to deal with critical deadlines in a very user-friendly way. With the vision of becoming the first-choice diagnostic among people in Eastern India for both routine and specialised tests, Suraksha has not only focused on the best technology but simultaneously on affordability.
A quarter century after Shekhar Kapur’s Bandit Queen generated a massive worldwide buzz following its premiere in Directors’ Fortnight in 1994, the epochal film’s producer, Bobby Bedi, has firmed up plans for a 20-episode web series on the life and death of Phoolan Devi, the dreaded Chambal dacoit-turned-Member of Parliament who was assassinated in the heart of Delhi in July 2001. The web series, titled ‘Phoolan Devi’, will be directed by Tigmanshu Dhulia, with Tannishtha Chatterjee taking on the role of the protagonist. Dhulia was the casting director of Bandit Queen. Also Read – Add new books to your shelfSpeaking on the sidelines of the 72nd Cannes Film Festival, Bedi reveals that the web series will go into production within the next few months. It will be spread out over two seasons of 10 episodes each. “The first season will end with Phoolan’s eight-year prison term, while the second will largely cover the years in the aftermath of her release,” he says. “Her prison term was extended by four years, but within two years of her release she became a Member of Parliament,” says Bedi. Also Read – Over 2 hours screen time daily will make your kids impulsive”Bandit Queen hinged on how a woman had to suffer huge indignities in rural India on account of being low caste. It focused on crushing caste oppression. In an urban setting, conversely, she demonstrated the political power of a low-caste woman,” says Bedi. For a long time, the New Delhi-based producer had toyed with the idea of doing a sequel to Bandit Queen. “Then the web space opened up and we realised it would be the best option because it allows the storyteller all the time to develop characters and settings,” he says. Bedi was sure from the very outset that he wanted Tannishtha for the role of Phoolan Devi. The actress came on board instantly once she was convinced that the web series would be completely unlike Bandit Queen in tone and substance. The new production is neither a sequel nor a remake the format is long enough to allow us to handle a wider canvas of the Phoolan story.
A quote to begin the story of Gloria Vanderbilt: “Our courts have their faults, as does any human institution, but in this country, our courts are the great levelers, and in our courts, all men are created equal.” A memorable quote from a book just as memorable, and based on it, a movie where Gregory Peck first spoke these words on screen only two years after Harper Lee’s Pulitzer winner novel To Kill a Mockingbird was published in 1960.Due to its didactic significance and the standard, it set for what a fair and unprejudiced trial ought to be, what is written on its pages today is considered a must-read for anyone who wishes to learn a thing or two about morality and justice. Although fictional, it is still a story that speaks better than any non-fiction about the coexistence of good and evil within us and how human beings cope with this duality that is their true nature. It speaks about the importance of moral education in life, but most importantly it speaks about a world where that moral education is lacking.Gloria Morgan Vanderbilt (widow of Reginald Vanderbilt) with her daughter Gloria Laura. 1926. Photograph. (Photo by Imagno/Getty Images)And in this world, although “the one place where a man ought to get a square deal is in a courtroom,” due to the fact that “people have a way of carrying their resentments right into a jury box,” more often than not, equality and justice are merely illusions covered as truth under the law and some end up being “more equal” than others as a result.As for the innocent, the children, they learn the cruel lesson of what “to kill a mockingbird” really means–the terrible sin of destroying someone’s life, someone’s innocence. Which is perhaps what happened to an innocent young girl who was thrust into the limelight during the two months long scandalous trial of a Kramer vs Kramer type battle for custody in the 1930s.Only this was not a fight for custody of Billy Kramer and where he should spend the nights and eat his favorite cereal, but for the 10-year-old heiress Gloria Laura Vanderbilt, and who should reap the benefits of her inheritance. Her great-great-granddad’s “little” fortune.Photo of Gloria Laura Vanderbilt, from a 1959 acting role on The United States Steel Hour.She was the daughter of Reginald Claypoole Vanderbilt, who was heir to a small portion of the wealth left behind by the business magnate Commodore Cornelius Vanderbilt, former owner of the New York Central Railroad, and one of the wealthiest Americans in history.Gloria’s daddy had a love for horses, founding a number of equestrian organizations in his lifetime. He also had a fondness for alcohol and this was his downfall– Cornelius Vanderbilt died from liver cirrhosis at the age of 45, when his daughter was only a year and a half old.The girl’s mom was a Swiss-born American named Maria Mercedes Morgan, daughter of a wealthy diplomat, Henry Hays Morgan Sr. In her early teens, Maria adopted the name Gloria.Reginald Claypoole VanderbiltShe and her twin sister, Thelma, received a privileged education in Europe and New York until their father gave permission for them, at the age of 16, to have their own apartment on Fifth Avenue. The two debutantes began to socialize with the upper class of the city almost instantly.The young, rich, and gorgeous identical twins were known as “The Magnificent Morgans” of New York, once described by fashion photographer Cecil Beaton as “alike as two magnolias…they diffuse a ‘Ouida’ atmosphere of hothouse elegance and lacy femininity.”Gloria Morgan Vanderbilt (left) with her identical twin, Thelma, Viscountess Furness, in 1955.Thelma married first and lived to have a life filled with scandals, alleged affairs and newspaper headlines to worry about. As for Gloria, the second magnolia, in 1923 she became the second wife of 42-year-old Reginald C. Vanderbilt, who died less than three years after their wedding.In his will, Gloria Morgan was appointed custodian of their daughter, Gloria Laura, and administrator of her $2.5 million inheritance. This is equivalent to around $35.4 million in 2018 (Bureau of Labor Statistics CPI inflation calculator), an amount that would allow them a comfortable income from investment interest.Gloria Morgan Vanderbilt with her daughter Gloria VanderbiltFor several years, mother and daughter lived in different glamorous cities in Europe and California. Mom was alleged to lead an expensive lifestyle, enjoying lavish all-nighters in the elite clubs of Paris, Cannes, Monte Carlo, and Hollywood, while little Gloria was cared for by her grandma, Laura Delphine Kilpatrick, Gloria Morgan’s mother, their in-house assistants, and the child’s nanny, Emma Kieslich.That was until her daughter caught tonsillitis and had to be brought back to New York for her tonsils to be removed. She stayed at her aunt’s home in the city for several months, receiving treatment and proper medical care.But then something happened. The girl’s aunt, Gertrude Vanderbilt Whitney and her legal representatives claimed the mother was unfit to care for her daughter–that she was inattentive and incompetent to care for a small child. The mother claimed her daughter had been kidnapped.Gertrude, a renowned sculptor and founder of the Whitney Museum of American Art, and at the time considered the wealthiest woman in America, allegedly refused to give her niece back to Gloria Morgan who filed for child custody as a result.Gertrude Vanderbilt WhitneyThus, the infamous Vanderbilt vs. Whitney – The Matter of Vanderbilt trial was set in motion and on October 1, 1934. The first hearing was held in front of hundreds of journalists, for judge John F. Carew, who in hindsight probably shouldn’t have, surprisingly let all the press inside his courtroom.Over the following weeks, what was supposed to be private family dispute solved behind closed doors turned into a media feeding frenzy and escalated into a courtroom circus charade. And 10-year-old Gloria got the full attention of the media, who were keen to write down and publish every single little detail about her, and her mother’s private life.The papers wrote all kinds of headlines about her mother’s alleged lesbianism, her debauched lifestyle and her cold indifference to her child.Gloria Vanderbilt in custody battle. Photo by Bettmann / Getty Images“People, people, people… Prince Langenburg and Mrs. Vanderbilt were found in bed together reading vile and wicked books… read all about it,” was perhaps the most enthralling.But contrary to reader’s intrigue and people’s craving for entertainment outside, inside the courtroom, it was the least pleasant thing a daughter could hear about her mother. She was present in the courtroom throughout the whole trial as evidence against her mother was presented.For instance, when nurse Emma Keislich was called to give her testimony, she spoke about Gloria Morgan’s character, her many lovers and how she was never there for her daughter. A maid testified that she found Lady Milford Haven (Princess Victoria of Hesse and by Rhine) in bed right next to Mrs. Vanderbilt “kissing her just like a lover.”The opposing side was just as crude and insensitive. They produced letters according to which a loving daughter was crying for her mama, explaining how much she misses her. And then, there were the accusations of how her aunt’s obsession with naked bodies could be a bad influence.Gloria Vanderbilt, photographed by Carl Van Vechten, March 3, 1955The mud-slinging and hearsay stories presented and accepted as evidence in court were all twisted into vivid interpretation by the New York press, who became strongly divided on who was the innocent party.On November 20th, a month and a half into the trial, judge Carew found the “perfect” solution: Let the child decide. A 10-year-old. The responsibility was all hers now. Young Gloria said she wished to live with her aunt. The very next day, Gertrude Whitney was awarded custody of her niece. The mother who was accused of neglecting her daughter had access on weekends and Christmas.The very next day The New York Journal American wittily yet untastefully wrote: “Rockabye baby, up on a writ, Monday to Friday Mother’s unfit. As the week ends she rises in virtue; Saturdays, Sundays, Mother won’t hurt you.”Gloria Vanderbilt, photographed by Carl Van Vechten, 23 May 1958.Ironically, her aunt lost interest immediately after the trial and disregarded her new ward completely. Or so the successful artist, fashion designer, mother of four and a mighty woman that Gloria Vanderbilt grew to be in the years that passed, later wrote in her autobiography Once upon a time: A true story in which she spoke about a childhood ruined and love never felt.Related Video:In her and her son’s touchingly intimate book, The Rainbow Comes and Goes: A Mother and Son On Life, Love, and Loss she also spoke about her experience in 1934, the hell she was put through during and after the trial, and how she was instructed and made to rehearse fabricated stories by her aunt’s legal team.Time passed and she learned to forgive all. For there is a saying that goes something like: “you never really understand a person until you consider things from his point of view–until you climb into his skin and walk around in it.”Related Article: The Breakers – Built by the Vanderbilts, it was the grandest mansion in NewportThough at the time, as things stand, no one even considered climbing into hers.
Here are Colin’s Week 8 Blazin’ 5 plays:Packers at Falcons (-2.5) Seahawks at Saints (+3)Chiefs at Colts (+2.5)Cardinals (+2.5) at PanthersEagles at Cowboys (-4.5)The Blazin’ 5 Prediction Podcast is available every Saturday through the end of the football season. Download and subscribe to it exclusively at TheHerdNow.com, iHeart Radio, Google Play, or iTunes. Don’t be a mark! It’s time for Colin’s Blazin’ 5 Prediction Podcast, and his weekly sit down with RJ Bell from Pregame.com to see where there’s agreement and disagreement from the Vegas wiseguys on his NFL Week 8 Blazin’ 5 picks.Colin is coming of his second 4-1 Blazin’ 5 in the last 3 weeks, and is an impressive 21-14 (66.7%) on the year. This week, he’s ready to take out the House like it was a recurring character from the season premiere of the Walking Dead.In Week 8, Colin likes the Falcons as a slight home favorite over Green Bay. The Saints and Indy getting points, at home in their domes. Road dog Arizona heading east to struggling Carolina. And, he’s finally a believer in Dallas, even giving 4.5 in the Sunday night game of the week against Philly. In Dak he trusts.So, what do the wiseguys say? Advertisement
Advertisement Paul George returned to Indiana for the first time since forcing his way out of town via trade last summer, and got a predictably hostile welcome back, at least by Indiana standards.PG13 heard it from the fans all night, including getting heckled during a free throw by an angry ex-fan… still wearing a Paul George jersey. This guy’s hatred of George is only eclipsed by his own lack of self awareness.Just let go dude, he’s gone. George had the last laugh with a 100-95 W.#Pacers fans booing Paul George…in a Paul George jersey ? #ThunderUp #NBA pic.twitter.com/1bkKt4jOsj— FootBasket.com (@FootBasketcom) December 14, 2017