Just imagine having all your Christmas shopping paid for. What’s even better wouldn’t it be great that the Taxman was the person who paid for it!TheTaxClinic.ie is the only tax practice in Donegal that specialises in claiming back your tax. Michael Coll from The Tax Clinic says “you can still claim back any overpaid tax for the years 2014, 2015, 2016 & 2017 but you must be quick as you will be unable to claim any overpaid tax from the year 2014 after the 31st of December 2018”.With millions of euro still going unclaimed each year it is just crazy that people are not checking if they are owed a tax refund he said.The Tax Clinic offer a NO Refund No Fee policy and check the last 4 years to see if there was any reliefs and tax credits due that were not claimed.As Chartered Tax Advisers we have the experience and knowledge to maximise any refund due. Just log onto to our website https://thetaxclinic.ie/tax-refunds/and complete the form and either email or post us the form so we can get to work.Letterkenny Office – 074 9160550Killybegs Office – 074 9732055Why not let the taxman pay for your Christmas? was last modified: November 22nd, 2018 by StephenShare this:Click to share on Facebook (Opens in new window)Click to share on Twitter (Opens in new window)Click to share on LinkedIn (Opens in new window)Click to share on Reddit (Opens in new window)Click to share on Pocket (Opens in new window)Click to share on Telegram (Opens in new window)Click to share on WhatsApp (Opens in new window)Click to share on Skype (Opens in new window)Click to print (Opens in new window) Tags:CHristmasdonegalRefundThe Tax Clinic
Eureka >> Just a few short years ago, the College of the Redwoods softball team was near extinction. Now, after a steady rise back to respectability, CR has its sights set on competing for a league title.The Corsairs finished with a 17-17 overall record last season. While a .500 record is the definition of average, it was a vast improvement for a program that had not had a .500 record or better since 2006 — having lost 25 or more games in each of previous nine seasons.As Corsairs head coach …
One of the early “amazing” stories reported in these pages concerned the startling observation that plants use a kind of “email” system in their own interplant “internet” (see 07/13/2001). What has been learned in the nine years since that story appeared? Quite a lot, and another fascinating article about plant communication appeared this week in Science Daily. Scientists at Duke, Cornell and the Universities of Helsinki and Uppsala confirmed that micro-RNAs are engaged in two-way communication as part of gene regulation between cells. A Duke team member said, “To our knowledge, this is the first solid evidence that microRNAs can move from one cell to another.” According to the article, this adds to the list of molecules involved in communication: hormones, proteins, and now micro-RNAs. The packets of information stored in these molecules regulate how tissues and organs are developed in leaves, roots and organs. Listen to one example of how proteins control a waterproofing layer:They also add a new element to the already complex interplay in Arabidopsis roots between two proteins, known as Scarecrow and Short-root, that Benfey’s team had described in earlier work. Those proteins interact and restrain one another to allow the assembly of a waterproofing layer of cells that ultimately enables plants to control precisely how much water and nutrients they take in. The researchers now show that Short-root moves from cells in the plant’s inner vasculature out into the waterproofing endodermis that surrounds it to activate Scarecrow. Together, those two transcription factors (genes that control other genes) activate microRNAs, known as MIR165a and 166b. Those microRNAs then head back toward the vascular cells, meeting and degrading another transcription factor (called Phabulosa) as well as other regulatory factors along the way.The two-way communication works across cell borders. The “internet” nature of these between-cell signals is essential for correct patterning of tissues, the article explained. Susan Haynes of NIH said, “This study provides important insight into how cells communicate positional information to orchestrate the complex process of tissue and organ development.” The article concluded by noting that the specific instances discovered here are most likely indicators of a general phenomenon that will be noticed throughout biology. Duke systems biologist Philip Benfey tacked on an evolutionary comment:He said there’s also reason to think that the specific regulatory interactions they’ve uncovered were key in the evolutionary transition from single-celled algae to land plants. “ “Formation of vascular tissue with a surrounding endodermal layer that acts as waterproofing was a key milestone in the evolution of land plants,” Benfey said. “Without a tube to conduct water, you can’t grow a tree or a sunflower.”This comment amounted to a requirement without a specification.It was really painful to reproduce Benfey’s Darwin malapropism in this otherwise fascinating entry. It’s kind of like having to endure someone telling an insensitive joke or belching during a speech. Let’s deal with it quickly and move along. This is another indiscretion from an evolutionist who has not learnt good manners. One cannot simply assume that miracles will occur on cue, simply because Mr. Darwin needs them. A single-celled alga needs a tube to conduct water. Yes, the tube needs a waterproofing layer, too. Without these requirements being met, you can’t grow a tree or sunflower. Fine; understood. But Mr. Benfey, who is going to snap his fingers and call for Tinker Bell to zap the alga with her mutation wand by your script? How many gazillion algae will have to die before one struggles to get the internet right and the email system working? Remember, you don’t believe in miracles or end-goals, so this all has to happen by an undirected process with each and every step producing survival value. LOL, LOL (Lots of Luck, Laugh out Loud). Ahem; back to our regularly scheduled celebration. Ladies and gentlemen, we call attention to this fine discovery by the teams at Duke, Cornell, Uppsala and Helsinki, and thank them for dazzling us with insights into another living design that predated our own. Here we thought we invented the internet, only to find it was there long before our feeble attempts at two-way packetized communication. My, what will we discover next!(Visited 29 times, 1 visits today)FacebookTwitterPinterestSave分享0
29 November 2012 South Africa achieved a massive R2.2-billion cost reduction in the R5.9-billion tender awarded to three pharmaceutical companies on Thursday for single-dose antiretroviral (ARV) drugs for the government’s HIV treatment campaign. Making the announcement in Pretoria, Health Minister Aaron Motsoaledi said that the majority of South Africans on state-sponsored ARV treatment for HIV would, from April 2013, need only one tablet instead of the current three per day. Motsoaledi said South Africa had managed to reduce the cost of the tender – for a single dose of the triple combination of tenofovir, entricitabine and efavirenz – by 38%, a massive saving of R2.2 billion.‘Means we can treat more patients’ The price of the three-in-one combination is R89.37, which Motsoaledi described as now the world’s lowest price for this product. The tender was awarded to South African companies Aspen Pharmacare and Cipla Medpro along with US firm Mylan Pharmaceuticals. “This new tender has moved from an original cost of R8.1-billion to R5.9-billion for two years,” Motsoaledi said. “This savings means we can treat more patients with the same budget.” Motsoaledi said, from April, all pregnant women who were HIV positive would be given the single dose combination during pregnancy and breast feeding, regardless of their CD4 count. At least 80% of patients on ARV treatment would also be able to switch to the single-dose combination, though Motsoaledi noted that those who couldn’t switch for any reason could still take individual ARV drugs.Benefits of the single-dose combination Motsoaledi said the single-dose combination had major benefits for patients, and not only in terms of compliance with the daily routine; the combination meant fewer side-effects, and easier logistics and storage. “The fixed dose combination … is more effective than dual therapy and has fewer side-effects for the pregnant mother, in addition to its convenient dosage regimen.” The drugs will be available in all 3 000 registered health facilities across the country, said Motsoaledi, adding that there would be no more delays in supply, as experienced with the previous supplier. “We have asked the suppliers to give us their commitment on this, and all three of them have done so.” Dr Francesca Conradie, clinical adviser for TB/HIV at Wits University’s Clinical HIV Research Unit, said the new combination would not be harmful to pregant mothers in any way. “Simplification of the tablets is so much easier for mothers, and it will lead to better results,” Dr Conradie said. UNAids country coordinator Dr Catherine Sozi commended South Africa for being able to access the effective drugs at a small price. “The reduction in cost is way beyond what we’ve hoped for,” Sozi said. Source: SANews.gov.za
A group of Christians were arrested by the police after they were found to be praying inside their house in Mathura. They were accused of “forcible conversion” of people in Irauli Gurjar village of Mathura. According to a local resident, Mamta, a Christian resident of the village, had invited fellow Christians in her house and was holding a prayer when they were attacked by her Hindu relatives. Mamta’s extended relatives filed a complaint alleging “forcible conversion” by Mamta and her friends. She denied any kind of conversion bid and had told the police that she and her friends were “holding prayer in her house as December was the month in which Jesus Christ was born.”According to Aditya Shukla, Superintendent of Police (Mathura rural) police received a complaint that a few Christians were trying to “convert people” in the village. “Seven people have been booked and arrested under IPC Section 295A (deliberate and malicious acts intended to outrage religious feelings). They have been sent to 14 days judicial custody by the local Mathura court,” Mr. Shukla said. Their bail petition is scheduled to be heard on Tuesday in the local court.Pramod Singh from Christian Legal Association told The Hindu that this “was an attempt to spread fear among the minorities and make them feel like second class citizens.”“All that these people were doing in Mamta’s house was holding prayer when they were attacked by Hindutva goons and arrested by the police. Since when holding prayer and practising one’s own religion became illegal in this country,” he said. “The Christian community in Mathura is scared. There is atmosphere of fear and apprehension about practising one’s faith. Christmas is approaching and Christians are scared of holding prayer,” he alleged.