ChargesOn Monday, March 5th, a 19-year-old male was arrested and charged in relation to a Burglary report. The man who remains in Police custody is scheduled to appear before the Magistrates Court on March 19TH, 2018. Facebook Twitter Google+LinkedInPinterestWhatsApp#TurksandCaicos, March 6, 2018 – Providenciales –ArrestsA man was arrested on South Caicos on Saturday, March 3rd, 2018, for the offence of wounding in connection with a report made to Police. The man was granted bail in the sum of USD$2000 and scheduled to return to the Police Station on South Caicos on March 7TH, 2018.A 39-year-old woman of Five Cays was arrested on Monday, March 5th, 2018 on suspicion of theft of USD$3000, at a major grocery store on Providenciales. The woman was granted bail in the amount USD$3500. Related Items: Burglary Police are investigating a Burglary that took place at a home in Blue Hills on March 2nd, 2018. The complainant reported to police that upon arriving at home he noticed two black flat screens and personal items missing.Police in South Caicos is investigating a Burglary that was reported on March 1st, 2018. Stolen were five packs of Peal and Seal and 19 pieces of wood. Value Unknown.Providenciales Police are investigating an Aggravated Burglary that took place on Monday, March 5th, 2018. The victim who was held up by gunpoint in her Kew Town home was robbed of her handbag, iPhone 8 valued USD$1000, Black Samsung valued USD$250, three passports, other identification cards and cash. The incident took place around 8:00 p.m. Facebook Twitter Google+LinkedInPinterestWhatsApp Accident The Royal Turks and Caicos Islands Police Traffic Department is investigating a two-car collision that took place on Monday, March 5th, 2018 on Paradise Road, Cooper Jack around 5:30 p.m. The silver Toyota Harrier received total damages, while the Honda Civic Ferio car received frontal damages. Both drivers were taken to Cheshire Hall Medical Centre for treatment.Release: RTCIPF
KUSI Newsroom KUSI Newsroom, LA MESA (KUSI) — An investigation was underway Friday into the suspicious death of a man at Sharp Grossmont Hospital in La Mesa, police said.The 58-year-old patient died a little before 2 p.m. Thursday at the hospital on Grossmont Center Drive, La Mesa police Lt. Vince Brown said.Police did not disclose a reason the death was considered suspicious but said no hospital employees are considered suspects.“Hospital staff reported the incident to La Mesa Police and officers responded to the hospital … at approximately 1:58 p.m.,” Brown said.“Detectives were later called to the scene. No hospital employees are considered subjects in this investigation.”Police did not release any other details, including the name of the person who died, but asked anyone with information about the incident to call La Mesa police at (619) 667-1400, San Diego County Crime Stoppers at (888) 580- 8477 or contact the agency online at sdcrimestoppers.org. Tipsters may remain anonymous and could be eligible for a reward of up to $1,000. Posted: December 29, 2017 Updated: 4:07 PM December 29, 2017 Police investigating suspicious death of Sharp Grossmont Hospital patient Categories: Local San Diego News Tags: La Mesa Police, Sharp Grossmont Hospital FacebookTwitter
Email On the brink of his May residency in NYC’s East Village, Escovedo talks songwriting, future plans, and how “Velvet Underground stole my whole consciousness”Nate HertweckGRAMMYs May 2, 2018 – 6:09 pm Tonight in New York’s East Village, acclaimed songwriter Alejandro Escovedo begins his May residency with the first of five shows in the neighborhood. The gritty, vibrant streets exploding with character and nuance suit his music perfectly. I tracked him down during rehearsal at the Bowery Electric, just a few doors down from where CBGB once stood, to ask him about his New York heroes, the making of his latest masterpiece Burn Something Beautiful, and what surprises he’s got in store for his May residency.”I lived right around the corner,” says Escovedo, reflecting on the East Village vibe. “I used to watch the Cramps cross the street every day to go to breakfast, which was at two in the afternoon, and they were amazing, it was just like this movie that opened up in front of you that was incredible. I just have so many memories here, and every time I come back I gravitate to the Lower East Side.”On this particular return to NYC, Escovedo has mapped out an ambitious month-long residency exploring a variety of formats and incorporating a fascinating list of guests such as singer/songwriter and musical historian Richard Barone, Nuggets collection compiler and Patti Smith guitarist Lenny Kaye, and New York Dolls guitarist Sylvain Sylvain. The residency kicks off with a show at Coney Island Baby on May 2 and closes with a special all-star band at Bowery Electric on May 30.”Back in Austin at the Continental Club, I would do residencies. I would always do something different, whether it was acoustic or feedback with strings,” says Escovedo. “The idea came to do one here when Jesse [Malin] and I were playing a lot of gigs together … I love the intimacy of these places, and I thought this would be a great place to do something like that. … I thought, ‘Well, let’s make every week a little different.'””We’re going to pick the songs together,” says Barone, who works and performs with Escovedo often. “We’ll be using our own songs with songs by artists we admire to tell our stories. It’s a biographical show … I’m going to do one of Alejandro’s songs that I always loved because I think it talks about both of us … it really tells our story.” Alejandro Escovedo and Richard BaronePhoto: Nancy Rankin Escovedo”Richard and I have always had that connection,” Escovedo says, talking about his mutual admiration for Barone, his long history with each special guest and teasing the residency’s finale with a knowing smile. His ambition harkens back to how the city of New York originally grabbed his heart.”When I was a kid in high school and that first Velvet Underground album came out, in our little town, Huntington Beach, California, you could go to any party amongst our group of friends and that record was playing, and we’d listen to it from the very beginning to the very end,” says Escovedo. “Growing up, my friends all wanted to travel to Europe … [but] I wanted to go to New York because the Velvet Underground was from New York.”Lou Reed’s influence on Escovedo’s work is clear, yet never feels imitative. As Barone puts it, “There’s a Lou Reed song for every emotion.” He and Escovedo produced a remarkable tribute to Reed during SXSW 2014 following his death.”There’s something about the way Lou Reed wrote about New York and what I was feeling at the time that made me want to experience that more than I wanted to experience the hippie thing that was happening in California,” says Escovedo. “That’s not to say I didn’t have interest in Buffalo Springfield and Love and all those bands. I did, but the Velvet Underground totally stole my whole consciousness.”Escovedo finally made it to New York in 1978 with his band the Nuns after they opened for the Sex Pistols’ historic last show at Winterland in San Francisco. His arrival in New York was, well, epic.”We had the consummate New York experience. We lived in the Chelsea hotel,” he says. “One of the first nights we were here I sat at a table with Deborah Harry, all of Blondie, the Nuns, Andy Warhol, [photographer] Francesco Scavullo, and George Clinton. We watched the Heartbreakers play at Max’s Kansas City. And that was kind of the beginning. Our first gig was at CBGBs — there’s David Byrne, there’s David Johansen. Everybody was there.”This punk-rock sentiment manifests itself in Escovedo’s songs even today — however, in a way that feels fresh as opposed to nostalgic. Case in point, his song “Johnny Volume” has a foot firmly planted in East Village legacy, but the other kicks forward with lyrics like, “I’m going down to Max’s, Fender Twin on 10/ I’m going back to St. Mark’s Place, start all over again.””I wrote it in Portland,” says Escovedo. “It was actually Scott’s initial song idea, and then we completed it. It’s about Johnny Thunders coming back and wanting to get it right this time — not that he got it wrong, but he wanted another shot at it. ‘I’m feeling so better/ It’s time to make amends,’ and ‘if you see me on the corner, I’m waiting on a friend’ was a reference to the Stones video we all saw [that was filmed] in the East Village.””Johnny Volume” is a live-wired cut from Escovedo’s latest album, 2016’s Burn Something Beautiful, which offers an exhibition in rock songwriting, production and arrangement. The album was produced by former R.E.M. guitarist Peter Buck and his Pacific Northwest-based partner in crime, bassist Scott McCaughey.”When I made Burn Something Beautiful,” says Escovedo, “I think I got back to where my heart really was with rock and roll, and I think I needed Scott and Peter to do that, and all the musicians who played on that record. … It was liberating.”Escovedo also talks with reverence and candor about his experience working with legendary producer Tony Visconti on his three albums prior to Burn Something Beautiful. Visconti is best known for his work with the incomparable David Bowie, one of Escovedo’s heroes.”[Bowie] passed away on my birthday,” he says. “David had been a major, major influence on me. Not only did he teach me about music, he taught me about art, and books, and theatre, and cinema, and mime, and Buddhism, and [he] taught us how to dress, [and] also how to be a man in a different way. He suddenly opened a door to a world that made it okay to be flamboyant, to be an actor in a way.”With equal parts imagination from Bowie and storytelling from Reed, Escovedo says his songwriting process is all about honesty and imagery.”This last record that I just finished, which is a concept record, it’s telling a story and so people say, ‘Well, the verses don’t rhyme,’ and then I go back and I listen to Lou — he’s telling a story,” says Escovedo. “The images are more important than whether the meter is correct in a poetic sense or lyrical sense. It’s more about the impact of the words and the story and the images that he creates.”I really don’t worry about the craft as much as I worry about making sure that I’m honest about what I’m trying to say and true to what I’m trying to say and not being pretentious in any way.””What sets [Escovedo] apart is how he continues to grow as an artist without losing track of his core musical identity,” says Barone. “He experiments … but it never loses that ethos of the punk era.”Looking forward, Escovedo says he’s writing a book with San Antonio-based author John Phillip Santos, telling his story in what he calls a “mythical memoir.” But he isn’t done making music yet.”I’m going to make another record with Peter and Scott, then I’m making a record of duets, and then I want to make one final record really encompassing the grandness of strings with distortion, almost like orchestrated metal machine music,” Escovedo says. “Then I think it’s time to put my feet up for a little bit. I travel hard and I’ve battled illnesses and whatnot, so it’s time to enjoy the fresh air.”As he runs through a career-spanning set during rehearsal the day before the first show of his May residency in the East Village, Escovedo couldn’t be more relaxed. He stops a song here and there to point out a string line for the guitar player to cover or to lock in a harmony part with his background vocalists, but you get the sense Escovedo is very comfortable yielding to the energy of rock and roll and putting faith in the musicians around him. He asks the band what song is next, they all casually call him “Al,” and his wife Nancy hangs out close by with their pup, Suki. From California to New York, Austin, Texas, and back again — for all of Escovedo’s travels — rock and roll is his true home.Catching Up On Music News Powered By The Recording Academy Just Got Easier. Have A Google Home Device? “Talk To GRAMMYs”Read more Facebook Alejandro Escovedo On New York, Lou Reed, David Bowie & More Twitter Alejandro Escovedo’s Rock & Roll Return To NYC alejandro-escovedo-new-york-lou-reed-david-bowie-more News
Enlarge ImageShots of cars in sand dunes never get old. Land Rover We’re slowly approaching the point where Land Rover will finally pull back the veil on its hotly anticipated 2020 Defender SUV. However, today isn’t that day, which means we’ll have to live with more cool pictures of a camouflaged Defender for now. Shucks.Land Rover on Friday released a new smattering of pictures showing the 2020 Defender tackling the sand dunes in Dubai. Part of the Defender’s testing program ahead of its official unveiling, Land Rover teamed up with the International Federation of Red Cross and Red Crescent Societies to give this little ute the ol’ what-for in an area where its buyers are likely to travel.Out in Dubai, the Defender didn’t just whip around the dunes. It also tackled hairpin curves on the Jebel Jais highway. Temperatures shot past the triple-digit mark, which makes it a great place to suss out the Defender’s high-temp behavior, as well. It also tackled altitudes well above the one-mile mark, ensuring its engine doesn’t choke itself out when the air gets thin. Share your voice Land Rover Tags 2018 Range Rover Velar: Effortless SUV elegance on- and off-road Land Rover Post a comment 33 Photos SUVs Luxury cars Future Cars 2020 Land Rover Range Rover Evoque review: Style, now with more substance Land Rover first announced the return of the Defender in late 2018, and it revealed that the model would finally return to the US, as well, following a 23-year absence. Its boxy good looks have remained hidden by camouflage, but Land Rover hasn’t been shy about throwing out a whole lot of teasers ahead of its anticipated debut, which could come as early as the Frankfurt Motor Show in September. Even rumors have been few and far between. The most notable one we’ve heard about, though, is that the Defender will be available in three sizes — 90, 110 and 130, with the smallest being a three-door model. We’ve also seen what appears to be the Defender’s interior thanks to some clever spy shots. If you can’t afford one, don’t worry, because Lego has a Technic Defender coming out, which should be significantly easier on the wallet. 2020 Land Rover Defender hits the dunes of Dubai More From Roadshow 0 2019 Land Rover Range Rover P400e review: A hard hybrid to recommend
The Proteas have been dubbed as ‘chokers’ for repeatedly failing to perform on the stage of major ICC tournaments. This time around, they were not looked upon as one of the favourites. The sudden retirement of AB de Villiers last year denied them the services of their most dynamic limited-overs player.However, the return to form of Hashim Amla in the practice match and the continuing success of Quinton de Kock gave the Proteas hope of producing a better effort this time than expected. Unfortunately for the Faf du Plessis-led team, while de Kock has failed to convert his good starts into big scores, Amla is yet to get an opportunity as he was forced to leave the field very early on in his innings.The bowlers have also disappointed by allowing both the teams they bowled to in the first two games to score over 300 runs. With Ngidi now also out of the third game of the tournament for Proteas, it’s an uphill task for them to stay in the hunt for the title. Ngidi won’t play against India due to injuryTwitter/ICCIf two losses in two matches are not bad enough, South Africa are now faced with another major problem. One of their key pacemen, Lungi Ngidi, has been declared unavailable for the team’s third match of the World Cup, against Indian on June 5.Ngidi suffered a hamstring problem during his team’s game match against Bangladesh at The Oval. This forced him to leave the field after having bowled just four overs in the game. South Africa were already plagued by injuries with Dale Steyn unable to play the first two matches and still not certain to take part in the fixture against India. On top of that, Hashim Amla suffered a blow to the head during the opening game of the tournament against England which caused him to retire hurt immediately and then sit out of the match against Bangladesh.Dangerous times for SAIf Steyn doesn’t recover and Amla too is unable to get back in the playing XI, South Africa’s campaign, already looking very unsteady, would be in danger of completely going off the rails.
Play Movie of nanoparticles moving through mucus. Credit: Schneider et al. Sci. Adv. 2017;3:e1601556 The nanoparticles, the team notes, were created using biodegradable materials that prior research found safe for internal use. Testing in mice, they report, showed the particle carriers stayed in the lungs for several hours—they also proved to be more effective than conventional therapies at reducing asthma symptoms such as irritation. The researchers suggest that MPPs could offer a better treatment plan for lung patients by providing a therapy that maintains drug levels in the lungs for longer periods of time, reducing the need for repeated dosing, which itself can cause lung irritation. PausePlay% buffered00:0000:00UnmuteMuteDisable captionsEnable captionsSettingsCaptionsDisabledQuality0SpeedNormalCaptionsGo back to previous menuQualityGo back to previous menuSpeedGo back to previous menu0.5×0.75×Normal1.25×1.5×1.75×2×Exit fullscreenEnter fullscreen More information: Craig S. Schneider et al. Nanoparticles that do not adhere to mucus provide uniform and long-lasting drug delivery to airways following inhalation, Science Advances (2017). DOI: 10.1126/sciadv.1601556AbstractMucoadhesive particles (MAP) have been widely explored for pulmonary drug delivery because of their perceived benefits in improving particle residence in the lungs. However, retention of particles adhesively trapped in airway mucus may be limited by physiologic mucus clearance mechanisms. In contrast, particles that avoid mucoadhesion and have diameters smaller than mucus mesh spacings rapidly penetrate mucus layers [mucus-penetrating particles (MPP)], which we hypothesized would provide prolonged lung retention compared to MAP. We compared in vivo behaviors of variously sized, polystyrene-based MAP and MPP in the lungs following inhalation. MAP, regardless of particle size, were aggregated and poorly distributed throughout the airways, leading to rapid clearance from the lungs. Conversely, MPP as large as 300 nm exhibited uniform distribution and markedly enhanced retention compared to size-matched MAP. On the basis of these findings, we formulated biodegradable MPP (b-MPP) with an average diameter of <300 nm and examined their behavior following inhalation relative to similarly sized biodegradable MAP (b-MAP). Although b-MPP diffused rapidly through human airway mucus ex vivo, b-MAP did not. Rapid b-MPP movements in mucus ex vivo correlated to a more uniform distribution within the airways and enhanced lung retention time as compared to b-MAP. Furthermore, inhalation of b-MPP loaded with dexamethasone sodium phosphate (DP) significantly reduced inflammation in a mouse model of acute lung inflammation compared to both carrier-free DP and DP-loaded MAP. These studies provide a careful head-to-head comparison of MAP versus MPP following inhalation and challenge a long-standing dogma that favored the use of MAP for pulmonary drug delivery. Play Movie of nanoparticles moving through mucus. Credit: Schneider et al. Sci. Adv. 2017;3:e1601556 Citation: Nanoparticles pass through mucus membranes in lungs to deliver pulmonary drugs (2017, April 6) retrieved 18 August 2019 from https://phys.org/news/2017-04-nanoparticles-mucus-membranes-lungs-pulmonary.html Journal information: Science Advances Lung problems impact the lives of millions of people. Such conditions include asthma, in which bronchi spasm, making it difficult to breathe; cystic fibrosis, in which over-production of mucus leads to blocking of bronchi; and COPD, in which obstructions form in bronchial passages. Fortunately, these types of ailments are all treatable to some degree, though they cannot be cured. For that reason, scientists continue to look for ways to improve current therapies.Currently, lung ailments such as cystic fibrosis, COPD and asthma are treated with inhaled drugs such as corticosteroids that adhere to the walls of air passages. In some instances, they are carried by what are known as mucoadhesive particles, (MAPs), but, as the researchers note, thick mucus often builds up on such passageways, lessening the effectiveness of the delivery system. In this new effort, the researchers took a different approach—rather than trying to make medicines that adhere do their job better, they turned to nanoparticles that are small enough to make their way through mucus membranes to the lining of the lungs themselves, offering direct medication application to affected areas. Called mucus-penetrating particles (MPP), they remain in the lungs, releasing medication for an extended period of time. The making of mucus in common lung diseases PausePlay% buffered00:0000:00UnmuteMuteDisable captionsEnable captionsSettingsCaptionsDisabledQuality0SpeedNormalCaptionsGo back to previous menuQualityGo back to previous menuSpeedGo back to previous menu0.5×0.75×Normal1.25×1.5×1.75×2×Exit fullscreenEnter fullscreen This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only. © 2017 Phys.org Explore further (Phys.org)—A team of researchers from multiple institutions in the U.S. has developed a new way to treat lung disease—using nanoparticles to transport chemicals through the thick mucus membranes that can coat pulmonary airways. In their paper published in the journal Science Advances, the team describes how they used particles small enough to move through holes in the mesh that makes up mucus to deliver helpful drugs.
Darjeeling: Even before the biggest soccer battle took to the ground in Russia, miles away, the World Cup was handed over to Bara Kakjhora United Club in Darjeeling on Sunday afternoon.As part of the “Darjeeling World Cup Town 2018,” Darjeeling North Point School Alumni Association (DNPSAA) had announced that a World Cup replica would be handed over to the best decorated area of the town on the day of the finals.”Places like Aloobari, J P Sharma Path (Pachpan Hatta), Employment Exchange area, Nimki Dara and others were well decorated. However, Bara Kak Jhora was not just decorated well but was done with a purpose. The uniqueness lay in the informative flexes that were put up,” stated Deven Gurung, President of the DNPSAA. Also Read – Speeding Jaguar crashes into Merc, 2 B’deshi bystanders killedThe detailed history of the world cup including winners over the years; pictures and history of legendary football players; a special display of Sunil Chettri for his achievement in the intercontinental cup, matching the 64 international goals to that of Messi.”However, the most touching display was on the legendary players of Darjeeling titled – 60’s legendary players of Darjeeling. They had put up photographs of famous players like Chandan Singh Raut, Benu Subba, Avay Gurung, Krish Dewan, Raju Rai, Kapil Thapa, Shyam Thapa and others. Thus, we zeroed in on Bara Kakjhora United Club (BKUC),” stated Gurung. Also Read – Naihati: 10 councillors return to TMC from BJPThe world cup replica was handed over to members of the BKUC in Darjeeling.”It’s our honest endeavor to educate Gen Y in Darjeeling about Darjeeling’s rich football past. This land has created legends. The youth have heard of Messi but not of local legends. It is our effort to revive the rich football past by promoting local football,” stated Yogesh Bomzan, member of the BKUC.DNPSAA had organised the event “Darjeeling the World Cup Town 2018,” to raise funds for the outreach program Fr Van Memorial Clinic on wheels.It was just a one-day event on 2nd June 2018.The event was very successful with thousands of people participating in the football parade followed by a variety entertainment programmes at Chowrasta.The Clinic on Wheels will provide medical facilities in far flung areas, catering specially to the marginalised section of society.
Suraksha Diagnostic Pvt Ltd (SDPL), a centre of innovation, is one of the trusted names in the healthcare industry with its unmatched international standards. Serving for almost three decades through its 41 centres all over the country is now proud to possess almost every possible diagnostic technology.Suraksha recently partnered with Clugenix – a San Francisco based biotech company focused on making translational genomics technologies accessible globally to the Indian population. Led by Dr Joydeep Mukherjee, a globally recognised, multiple award-winning researcher in oncology and infectious diseases genomics in Toronto and UCSF, Cluegenix will make available to Suraksha the latest developments in Molecular Biology. Also Read – Add new books to your shelfMore importantly, together they will work to set up the protocols for the Indian population in genomics. A lot of this research being done in the house will help to reduce the cost of these expensive tests considerably. They will be launching to design the Next-Gen Sequencing panel for Breast Cancer for Indian women as their first research project out of this JV. Suraksha has come up with ‘Aptio’ automation, the robotic track, as a unified and complete solution to its expanding need. The track is completely AI enabled and runs without human interference. It provides the best therapeutic turnaround time in the industry. In an emergency, it can churn out a report in less than a minute. The entire system is One flow One Touch. Also Read – Over 2 hours screen time daily will make your kids impulsiveThey have laid a track that can do Biochemistry and Haematology at the same time. ‘Aptio’ connects numbers of diagnostic analysers even of different principles or discipline. Its automated sample loading and handling (tube sorting, offloading) feature helps lab staffs to from time-consuming, low-value tasks. Staffs are also spared from segregating different types of samples (EDTA whole blood, serum, urine), one from each other. The track reduces pre-analytical errors by detecting any mismatch between test request and tube type, identifies problem samples and draws the attention of the operator. Simultaneous STAT and routine testing on a single track with optional front-loading for urgent or low volume samples to instruments enable lab supervisors to deal with critical deadlines in a very user-friendly way. With the vision of becoming the first-choice diagnostic among people in Eastern India for both routine and specialised tests, Suraksha has not only focused on the best technology but simultaneously on affordability.